Currently Running and Published Studies

Below is a selection of the studies currently running at the Imperial CRF that have closed recruitment, as well as those that have been completed and published. 

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ACH Trial

Research, Studies
We are recruiting to a phase 2 study assessing the effects of a complement inhibitor on C3 glomerulopathy and immune-complex MPGN.
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Mi-Part

Research, Studies
We are looking for men and women over 18 years old with Psoriatic Arthritis. The purpose of this study is to: Identify, group and mark the…
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Repromet

Research, Studies
We are looking for healthy men, who do not take any medication and do not smoke, aged 18-40 with a BMI of 18.5-40. Eligible participants will…
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Diabetes Research Study

Dietetics, Research, Studies
We are running a research study to understand the role of gastric bypass surgery, hormones, and diet on the development of diabetes mellitus or 'sugar' diabetes.…
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Ad4HIV

Research, Studies
Healthy males and females aged 18 to 50 required for a study being carried out to develop vaccines to combat HIV. The study will involve 12…
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Kisspeptin fMRI 2

Research, Studies
Healthy males under 36 years old required for a study investigating the effects of a naturally occurring hormone (called kisspeptin) on human brain function. You will…
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UDCA Part 2

Dietetics, Research, Studies
Males and females aged 18 to 65 with diabetes or pre-diabetes on the waiting list for bariatric surgery. The study involves attending our research unit for…
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GRAVITAS

Research
GLP-1 Receptor Agonist interVention for poor responders after barIAtric Surgery: The GRAVITAS trial
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I HART CGM

Research, Studies
Impact on Hypoglycaemia Awareness of Real Time CGM and Intermittent Continuous Glucose Data
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Microprobe Sensor

Research
This involves two visits to the research unit at Hammersmith Hospital to assess the new device. Each visit will be for six hours to wear the…
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BAC-alc

Research
Abstinent alcohol-dependent volunteers wanted for a study investigating brain receptors in alcohol addiction. You will receive a medication called baclofen, or a placebo, and have a…
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LSD-fMRI/MEG (Published)

Research
Using fMRI to investigate the effects of LSD on brain activity in healthy hallucinogen-experienced volunteers.
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NK3R Study

Research, Studies
Peri- or menopausal women aged 40-62 years old having regular hot flushes/night sweats
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VAC053

Research
We are looking for healthy volunteers aged 18-50 to take part in our malaria vaccine trial. The trial involves up to 15 visits to our outpatient…
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GHADD

Research, Studies
We are investigating the effects certain gut hormones (hormones that are produced in the stomach and intestine) have on eating and addictive behaviours in people who…
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EBL05 Ebola Vaccine Trial

Research
This is a study to assess the safety and immunogenicity of two Ebola vaccine candidates: ChAd3-EBO Z and Ad26.ZEBOV.
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fMRI Obesity

Research
We do not understand fully why people overeat or the mechanisms in the brain which influence how successful people are at losing weight.
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Mycoprotein

Research
We are investigating the effect of eating various levels of mycoprotein on feelings of appetite and levels of gut hormones.
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PP1420

Research
We are looking for healthy, overweight male volunteers aged 18-50 for a study looking at a new drug for obesity.
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Kiss IVF (Published)

Research
Infertility affects 1 in 6 couples in the UK, which is estimated to amount to 3.5 million people.
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Protein Rich

Research
We are looking for volunteers aged 25-70 who have a BMI between 27-35 for a study looking at whether a high-protein low-energy diet (using meal replacement…
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Qutenza (Published)

Pain, Research
Treprostinil sodium (Remodulin) solution for infusion is a prostacyclin analogue approved for the treatment of patients with pulmonary arterial hypertension (PAH) in functional class II-IV.
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Transeuro

Neurology, Research
The aim of this multi-centre European consortium (Transeuro) funded by an FP7-EU grant is to conduct a new round of neural cell transplantation clinical trials in…
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PRC-REMS

Neurology, Research
Patient Research Cohort –Rapidly Evolving Multiple Sclerosis (PRC-REMS) study. We are close to completing patient recruitment (n = 178 out of target n = 200) in…
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Nicotinamide (Vitamin B3) in Friedreich’s ataxia

Neurology, Research
Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease. FRDA is the most frequent inherited ataxia, which usually presents in childhood and is characterized by impaired…
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Obesity Surgery, fMRI Obesity and Preterm MRI

Metabolic Medicine / Obesity, Research
Dr. Tony Goldstone, Imperial College London, uses magnetic resonance imaging (MRI) of the brain to identify how obesity, gut hormones and treatments for obesity modify the…
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InflammALC

Mental Health, Research
This study aims to investigate whether there is inflammation in the brains of alcoholics around the time of detoxification and whether this contributes to brain damage…
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ICCAM

Mental Health, Research
This program of research tackles the brain mechanisms underpinning two of the most prevalent and costly addictions in the UK, those to opioids (heroin) and to…
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GE-PET ANGIO, IFIN and FIND4

Cancer, Research
The Imperial College London Comprehensive Cancer Imaging Centre (ICLCCIC), under the Directorship of Prof Eric Aboagye, has a well-established affiliation with the NIHR/Wellcome Trust Imperial CRF…
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Ferinject

Cardiovascular, Research
Previous studies of patients with pulmonary arterial hypertension attending the hospital have shown that many are iron deficient, but not anaemic.
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DCA Study

Cardiovascular, Research
Pulmonary arterial hypertension is an uncommon disease with few treatment options.
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LCD Study

Dietetics, Research
Bariatric surgery is still a reasonably new area and more research is needed to decrease the risks of complications and improve the outcomes of the surgery.